Hakkımda | Doç. Dr. Emre Bakırcıoğlu
 
Üroloji & Androloji
Erkek Cinsel ve Üreme Sağlığı
Emre Bakırcıoğlu - Özgeçmiş

Özgeçmiş

1967 yılında İstanbul'da doğdu. 1984-1990 yıllarında İ.Ü. Cerrahpaşa Tıp Fakültesi’nden mezun oldu. 1991-1992 yıllarında Şebinkarahisar’da pratisyen hekim olarak mecburi hizmet yaptı. 1992-1997 yıllarında Haydarpaşa Numune Hastanesi Üroloji Bölümü’nde uzmanlık eğitimini tamamladı. Uzmanlık eğitiminin son 6 ayında Kaliforniya Üniversitesi, San Francisco (UCSF) Üroloji Depatmanı'nda Dr. Tom Lue'nun gözetiminde Erektil Disfonksiyon ve Nöroüroloji konularında araştırma görevlisi olarak çalıştı. Uzmanlık eğitimi bitiminde yine UCSF Üroloji Bölümü’nden aldığı bursla araştırma görevlisi olarak çalışmalarıma devam etti. Erektil disfonksiyon, üriner sistem diversiyonlarında kullanılabilecek aseluler matriks materyali ve idrar kaçırma (stress inkontinans)  modelleri oluşturarak ve bu modeller üzerinde fizyopatolojik değişikliklerin incelenmesi üzerinde bir çok çalışmalar yaptı.
İnfertilite üzerinde 2001 yılında Baylor Medical School'da Dr. Larry Lipshultz ve 2002 yılında New York Cornell Üniversitesi’nde Dr. N. Peter Schlegel'in yanında gözlemci doktor olarak bulundu.

Üye olduğu Mesleki Dernekler ve Kuruluşlar:
Türk Tabibleri Birliği, Türk Üroloji Derneği, Ürolojik Cerrahi Derneği, Türk Androloji Derneği, Üreme Sağlığı ve İnfertilite Derneği, Üreme Tıbbı ve Cerrahisi Derneği
European Association of Urology, Urology American Urological Association (AUA), American Society for Reproductive Medicine (ASRM), Society for Male Reproduction and Urology (SMRU)

Ödüller
2000 Lapides Essay Contest: Second Place Winner
2000 Lapides Essay Contest: Second Place Winner
American Urological Association 2000, Atlanta
2000 Yamanuchi Prize winner 'The best abstract in impotence category'
2000 Yamanuchi Prize winner 'The best abstract in impotence category'
American Urological Association 2000, Atlanta
1999 Bard-Preis Award
1999 Bard-Preis Award
2000 Lapides Essay Contest: Second Place Winner
2000 Lapides Essay Contest: Second Place Winner
American Urological Association 2000, Atlanta
1997 Lapides Assay Contest 'Honorable Mention'
1997 Lapides Assay Contest 'Honorable Mention'
1997 Lapides Assay Contest 'Honorable Mention'
Bilimsel Makaleler

ULUSLARARASI DERGİLERDE YAYINLANAN MAKALELER
 
1.     Dahiya R., Lin, A., Bakircioglu M.E., Huang S-T and Lue T.F.: mRNA and protein expression of nitric oxide synthase and adrenoceptor alpha-1 in young and old rat penile tissues. Br J Urol. 1997 Aug;80(2):300-6.
 
2.     Lin C.-S., Lau A., Bakircioglu E., Tu R., Wu F., Week S., Nunes L. and Lue T.F.: Analysis of neuronal nitric oxide synthase isoform expression and identification of human nNOS-m. Biochem Biophys Res Commun. 1998Dec 18; 253(2):388-94.
 
3.     El-Sakka A., Hassan M.U., Bakircioglu M.E., Pillarisertty R.J., Dahiya R., and Lue T.F.: Possible molecular mechanisms of cryoablation-induced impotence in a rat model. Urology. 1998 Dec;52(6):1144-50.
 
4.     El-Sakka A. I., Bakircioglu M.E., Bhatnagar R. S., Yen T. S., Dahiya R., and Lue T. F. The effects of colchicine on a Peyronie's-like condition in an animal model. J. Urol. 1999 Jun;161(6):1980-3.
 
5.     Bakircioglu M.E., Sievert K.-D., Lau A., Lin C.-S., and Lue T.F.:  The Effect of Pregnancy and Delivery on the Function and Ultrastructure of the Rat Bladder and Urethra. Br. J. Urol. 2000 Feb;85(3):350-61.
 
6.     Sievert K.-D., Bakircioglu M.E., Nunes L., Tu R., Dahiya R., and Tanagho E.A.: Homologous Acellular Matrix Graft for Urethral Reconstruction in the Rabbit: Histologic and Functional Evaluation. J. Urol.2000 Jun;163(6):1958-65.
 
7.     Bakircioglu M.E., Hsu K., El-Sakka A., Sievert K.-D., Lin C.S., and Lue T.L.: The effect of a Chinese herbal medicine mixture on a rat model of hypercholesterolemic erectile dysfunction. J Urol. 2000 Nov;164(5):1798-1801.
 
8.     Bakircioglu M.E., Lin C.S., Fan P., Sievert K.-D, Kan Y.W., and Lue T.F.: The effect of adeno-associated virus-mediated brain-derived neurotrophic factor in an animal model for neurogenic impotence. J. Urol. 2001 Jun (6 Pt 1);165:2103-2109.
 
9.     Sievert K.D., Wefer J., Bakircioglu M.E., Nunes L., Dahiya R., and Tanagho E.A.: Heterologous acellular matrix graft for recontriction of the rabbit urethra: histological and functional evaluation. J. Urol. 2001 Jun;165(6 Pt 1):2096-2102.
 
10.  Sievert K.-D., Emre Bakircioglu M., Tsai T., Dahms S. E., Nunes L., and Lue T. F.: The effect of simulated birth trauma and/or ovariectomy on rodent continence mechanism. Part I: Functional and Structural Change. J Urol. 2001 Jul;166(1):311-7.
 
11.  Bakircioglu M.E., Sievert K.-D., Nunes L., Lau A., Lin C.-S., and Lue T.F.: Decreased trabecular smooth muscle and caveolin-1 expression in the penile tissue of aged rats. J. Urol 2001 Aug.; 166(2):734-8.
 
12.  Wefer, J., Sekido N., Sievert K.-D., Wefer A. E., Nunes L., Bakircioglu M. E., Dahiya R., and Tanagho E. A.: Tunica albuginea acellular matrix graft for penile reconstruction in the rabbit: A model for treatment of Peyronie’s disease. BJU Int. 2002 Aug; 90:326-331.
 
13.  Kahraman S., Findikli N., Berkil H., Bakircioglu E., Sertyel S. and Biricik A.: Results of preimplantation genetic diagnosis in patients with Klinefelter’s syndrome. RBM online 2003 Oct.; 7 (3): 346-352.
 
14.  Sievert K.-D., Bakircioglu M.E., Tsai T., Nunes L., Lue T.F.: The effect of labor and/or ovariectomy on rodent continence mechanism--the neuronal changes.World J Urol. 2004 Oct.; 22(4):244-50.
 
15.  Bakircioglu M.E., Erden H.F., Kaplancan T., Cıray N., Bener, F., Bahceci M.: Aging may adversely affect testicular sperm recovery in patients with Klinefelter’s syndrome. Urology 2006 Nov.; 68 (5):1082-1086.
 
16.  Bakircioglu M.E., Erden H.F., Ciray H.N.,  Bayazit N., Bahceci M.: Gonadotrophin therapy in combination with ICSI in men with hypogonadotrophic hypogonadism. Reproductive BioMedicine Online 2007 Aug.; 15 (2): 156-160.
 
17.  Bakircioglu M.E., Ulug U, Erden H.F., TosunS., Bayram A., Ciray N., Bahceci M.: Klinefelter’s syndrome: does it confer a bad prognosis in the treatment of nonobstructive azoospermia? Fertil Steril. 2011 Apr;95(5):1696-9.
 
18.  Bakircioglu M.E., Tulay P., Findikli N., Erzik B., Gültomruk M., Bahceci M.: Successful sperm recovery and IVF treatment in a man with Leydig cell hypoplasia J Asist Reprod Genet. 2014 Jul;31(7):817-21.

19.  Ramasamy R., Bakircioglu M.E., Cengiz C., Karaca E., Scovell J., Jhangiani S. N., Akdemir Z.C., Bainbridge M., Yu Y., Huff C., Gibbs R. A., Lupski J. R., Lamb D. J. Fertil Steril 2015 Aug;104(2):286-91.Whole-exome sequencing identifies novel homozygous mutation in NPAS2 in family with nonobstructive azoospermia.

20.  Okutman O., Muller J., Baert Y., Serdarogulları M., Gultomruk M., Piton A., Rombaut C., Benkhalifa M., Teletin M., Skory V., Bakircioglu E., Goossens E., Bahceci M., Viville S. Exome sequencing reveals a nonsense mutation in TEX15 causing spermatogenic failure in a Turkish family. Hum Mol Genet. Oct 1;24(19):5581-8.

21. Okutman O, Muller J, Skory V, Garnier JM, Gaucherot A, Baert Y, Lamour V, Serdarogullari M, Gultomruk M, Röpke A, Kliesch S, Herbepin V, Aknin I, Benkhalifa M, Teletin M, Bakircioglu E, Goossens E, Charlet-Berguerand N, Bahceci M, Tüttelmann F, Viville S. A no-stop mutation in MAGEB4 is a possible cause of rare X-linked azoospermia and oligozoospermia in a consanguineous Turkish family. J Assist Reprod Genet. 2017 May;34(5):683-694. 

22. Clavijo RI, Bakircioglu E, Ramasamy R. Re: Predictive Factors for Sperm Recovery after Varicocelectomy in Men with Nonobstructive Azoospermia: K. Shiraishi, S. Oka and H. Matsuyama. J Urol. 2017 May 2. pii: S0022-5347(17)40344-2
 
ULUSAL DERGİLERDE YAYINLANAN MAKALELER
 
1.     Gürdal M., Şengör F., Erdoğan K., Bakırcıoğlu E., Çelik B.: Erektil disfonksiyonun değerlendirilmesinde renkli Doppler ultrasonografi. PTT Hastanesi Tıp Dergisi 1994 16:3, 253-8.
 
2.     Yılbaz N., Şengör F., Taşcıoğlu J., Erol A., Bakırcıoğlu E.: Üretrit semptomları olan hastalarda gonokoksik ve nongonokoksik üretrit etkenleri. PTT Hastanesi Tıp Dergisi 1996, 18(1):401-2.
 
3.     Bakırcıoğlu E., Yücebaş E., Kanberoğlu H., Şengör F.: Penis fraktürü ile birlikte komplet üretral rüptür. Türk Üroloji Dergisi 1996, 22:2, 193-5.
 
4.     Bakırcıoğlu ME, Berkil H., Biricik A., Sertyel,S., Fındıklı N., Kahraman S.: Klinefelter sendromlu hastalarda mikrodiseksiyon TESE (mikro TESE) ve preimplantasyon genetik tanı (PGT) sonuçlarımız. Türk Üroloji Dergisi 2003, 29:4, 429-435.
 
5.     Bakırcıoğlu, ME, Alıcı B.: Testis kanserli hastalarda sperm dondurma ve infertilite. Üroonkoloji Bülteni 2014, 13:176-181.

Yurtdışı Bildiriler

1.     Bakircioglu M.E., et al.: Value of color doppler sonography in the diagnosis of venogenic impotence. VII World Meeting on Impotence. San Francisco, California. November 03- 07, 1996.
2.     Bakircioglu M.E., et al.: Alterations of smooth muscle component and caveolin-1 expression with aging in rat penile tissue. AUA 94th Annual Meeting. Dallas, Texas. USA, May 1-6, 1999.
3.     Sievert K.-D., Bakircioglu M.E., Tsai T., Herwig R., Hertle L., and Lue T.F.: Simulated birth trauma and/or ovariectomy as causes of the neuronal changes in rodent continence mechanism. Dutch Urological Association 5th International Congress, Groningen, Holland. September 1999.
4.     Sievert K.-D., Bakircioglu M.E., Herwig R., Hertle L., and Lue T.F.: Functional and ultrastructural changes in rat bladder, bladder neck and urethra muscle caused by birth trauma and/or ovariectomy. Dutch Urological Association 5th International Congress, Groningen, Holland. September 2-4, 1999.
5.     Sievert K.-D., Bakircioglu M.E., Tsai T. Wefer J., Herwig R., Nunes L., Hertle L., and Lue T.F.: Homologous acellular urethral matrix graft for urethral reconstruction in the rabbit. The Third World Congress on Urological Research, Paris, France. September 30 -October 3, 1999.
6.     Sievert K.-D., Bakircioglu M.E., Herwig R., Hertle L., and Lue T.F.: Functional and ultrastructural changes in rat bladder, bladder neck and urethra muscle caused by birth trauma and/or ovariectomy. The Third World Congress on Urological Research, Paris, France. September 30 -October 3, 1999.
7.     Sievert K.-D., Bakircioglu M.E., Herwig R., Hertle L., and Lue T.F.: Simulated birth trauma and/or ovariectomy as causes of neuronal changes in rodent continence mechanism. The Third World Congress on Urological Research, Paris, France. September 30 -October 3, 1999.
8.     Sievert K.-D., Wefer J., Bakircioglu M.E., Dahiya R., Herwig R., Hertle, L., and Lue T.F.: Reconstruction of the rabbit urethra with an acellular matrix (AUM) xenotransplantation. The Third World Congress on Urological Research, Paris, France. September 30 -October 3, 1999.
9.     Bakircioglu M.E., et al.:  The effect of pregnancy and delivery on the function and ultrastructure of the rat bladder and urethra. AUA 75th Western Section Meeting, Monterey, California. September 26-29, 1999.
10.  Sievert K.-D., Wefer J., Bakircioglu M.E., Nines L., Dahiya R., and Tanagho E.: Acellular urethral matrix (AUM) Xenotransplantation compared with homograft AUM for reconstriction of the rabbit urethra. AUA 75th Western Section Meeting, Monterey, California. September 26-29, 1999.
11.  Sievert K.-D., Bakircioglu M.E., Tsai T. Wefer J., Nunes L., and Lue T.F.: The neuronal changes of simulated birth trauma and/or ovariectomy on rodent continence mechanism. AUA 75th Western Section Meeting, Monterey, California, September 26-29, 1999.
12.  Bakircioglu M.E., et al.: The Effect of Pregnancy, Delivery, Simulated birth trauma and/or Ovariectomy on the Function and Ultrastructure of the Rat Bladder and Urethra. International Bladder Symposium. November 1-5 1999, Washington.
13.  Bakircioglu M.E., et al: The effect of adeno-associated virus-mediated brain-derived neurotrophic factor in an animal model for neurogenic impotence. AUA 95th Meeting Atlanta, Georgia. April 29-May 4, 2000. ‘The best abstract in impotence category’ Yamanuchi prize winner
14.  Lee M.-C., El-Sakka A., Bakircioglu E., Lin C.-S., Lue T.F.: The effect of vascular endothelial growth factor on a rat model of arterial impotence. AUA 95th Meeting Atlanta, Georgia. April 29-May 4, 2000.
15.  Wefer J., Sekido N., Bakircioglu M.E., Nunes L., Dahiya R., Tanago E.A.: Acellular tunica albuginea graft for functional penile reconstruction in rabbits: A model for treatment of Peyronie’s disease. AUA 95th Meeting Atlanta, Georgia. April 29-May 4, 2000.
16.  Bakircioglu M. E., et al.: The effect of adeno-associated virus-mediated brain derived neurotrophic factor in an animal model for neurogenic impotence. 9th World Meeting on Impotence Research. Perth, Western Australia. November 26-30, 2000.
17.  Lee M.-C., El-Sakka A., Bakircioglu M. E., Lin C.-S., and Lue T.F.: The effect of vascular endothelial growth factor on a rat model of traumatic arteriogenic erectile dysfunction. 9th World Meeting on Impotence Research. Perth, Western Australia. November 26-30, 2000.
18.  Bakircioglu E., et al.: Can histology of testis predict sperm recovery by microdissection TESE in patient with azoospermia? 5th. Kongress der Deutsch-Turkischen Gynakologengesellschaft II. Internationaler Kongress fur Reproduktionsmedizin Antalya, Turkey, May 16-20, 2003.
19.  Biricik A., Berkil H., Karadayi H., Bakircioglu E., Kahraman S., Fiorentino F.GGGGGGGggggGGGGGGGG, Sertyel S., Donmez E., Vanlioglu F., Karlikaya G.: Molecular and cytogenetic analysis results in severe infertile males and their prognostic value for PGD in Turkish Population. 5th International Symposium on Preimplantation Genetics, Antalya, Turkey, June5-7, 2003.
20.  Sertyel S., Bakircioglu E., Kahraman S., Biricik A., Donmez E., Findikli N., Unal S., Yelke H., Melil, S., Karagozoglu H., Berkil H.: Outcome of PGD in cases of severe sperm morphological defects. 5th International Symposium on Preimplantation Genetics, Antalya, Turkey, June5-7, 2003.
21.  Bakircioglu E., et al.: Preimplantation genetic diagnosis for Klinefelter’s Syndrome: Evidence for increased chromosomal abnormalities. 5th International Symposium on Preimplantation Genetics. Antalya, Turkey, June 5-7, 2003.
22.  Bakircioglu E., et al: Comparison of testicular sperm extraction of microdissection and multi-biopsy techniques in patients with Klinefelter’s Syndrome. 19th Annual Meeting of the ESHRE, Madrid, Spain 2003.
23.  Biricik A., Berkil H., Karadayi H., Bakircioglu E., Kahraman S., Guney I. And Benkhalifa M.: Chromosome and Y deletion analysis of non-obstructive azoospermic males and sperm retrieval technique. 19th Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE), Madrid, Spain 2003.
24.  Bakircioglu M. E., et al.: Comparison of two TESE procedures and PGD outcomes for patients with Klinefelter's Syndrome. 59th Annual Meeting of the American Society for Reproductive Medicine (ASRM), San Antonio, USA, October 11-15, 2003
25.  Bakırcıoglu M. E., et al.: Comparison of intracytoplasmic injection outcomes using ejaculated or testicular sperm in patients with cryptozoospermia. 99th Annual Meeting of the American Urological Association (AUA), San Francisco, USA, May 8-13, 2004.
26.  Berkil H., Bakırcıoglu M. E., Biricik A., Karadayı H., Kahraman S.: Molecular and cytogenetic analysis in azoospermic males and their prognostic value for sperm retrieval in Turkish population. 99th Annual Meeting of the American Urological Association (AUA), San Francisco, May 8-13, 2004.
27.  Bakırcıoglu M. E., et al.: Comparison of intracytoplasmic sperm injection outcomes for patients with globozoospermia. 99th Annual Meeting of the American Urological Association (AUA), San Francisco. May 8-13, 2004.
28.  Bakircioglu M. E., et al.: Microdissection testicular sperm extraction (TESE) outcomes in patients with azoospermia and cryptozoospermia for intracytoplasmic sperm injection. 60th Annual Meeting of the American Society for Reproductive Medicine (ASRM), Philadelphia, October 10-16, 2004.
29.  Bakircioglu M. E., et al.: Efficiency of microdissection TESE in different histological patterns of nonobstructive azoospermia. 13th World Congress on in Vitro Fertilization – Assisted Reproduction & Genetics, Istanbul, Turkey, May 26 – 29, 2005.
30.  Bakircioglu M. E., Eet al.: Microdissection TESE outcomes for patients with Klinefelter’s syndrome. 13th World Congress on in Vitro Fertilization – Assisted Reproduction & Genetics, Istanbul, Turkey, May 26 – 29, 2005.
31.  Bakircioglu M. E., et al.: Comparison of Intracytoplasmic Sperm Injection outcomes in patients with cryptozoospermia and severe oligozoospermia. Conjoint Annual Meeting ASRM and CFAS, Montreal, Canada, October 15-19, 2005.
32.  Bakircioglu M. E., et al.: Medical therapy in combination with intracytoplasmic sperm injection in men with hypogonadotropic hypogonadism. 22nd Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE), Prague, Czech Republic, June 18-21, 2006.
33.  Bakircioglu M. E. et al.: Infertility treatment of men with nonmosaic Klinefelter’s syndrome. 102th Annual Meeting of the American Urological Association (AUA), Anaheim,  May 8-13, 2007.
34.  Bakircioglu M. E., et al.: Microdissection Testicular Sperm Extraction Outcomes in Different Etiological Patterns of Nonobstructive Azoospermia. 63rd  Annual Meeting ASRM, Washington DC, October 13-17, 2007.
35.  Bakircioglu M. E., et al.: The combination of gonadotrophin therapy and intracytoplasmic sperm injection in the treatment of hypogonadotrophic hypogonadism.64th Annual Meeting ASRM, San Francisco, CA, November 8-12, 2008.
36.  Bakircioglu M. E.et al: Comparison of intracytoplasmic sperm injection in patients with nonobstructive azoospermia, cryptozoospermia and severe oligozoospermia. 64th Annual Meeting ASRM, San Francisco, CA, November 8-12, 2008.
37.  Bakircioglu M. E., et al.: Comparison of ICSI outcomes between nonobstructive azoospermic males with normal chromosome structure and Klinefelter’s syndrome. 65th Annual Meeting ASRM, Atlanta, GA 17-21 October, 2009.
38.  Bakircioglu M. E., et al.: Klinefelter’s syndrome: Is it a bad prognosis in infertility treatment of non-obstructive azoospermia. 105th Annual Meeting of the American Urological Association (AUA), San Francisco,  May 29-June 3, 2010.
39.  Bakircioglu M. E. et al.: Comparison of controlled ovarian hyperstimulation cycles using testicular spermatazoa or ejaculated spermatozoa for assisted fertilization. The 5th symposium of “Infertility and Gynecological Endoscopy in Kosova”. Gjakové, April 16, 2011.
40.  Bayram A, Sahin O, Coban M, Bakircioglu E, Ciray N, Ulug U, Tosun S, Bahceci M: Comparison of pregnancy and implantation rates of frozen-thawed embryos fertilized with fresh or frozen-thawed testicular sperm and fresh ejaculated sperm of normospermic and oligospermic patients. 67th Annual Meeting ASRM, 15-19 October 2011, Orlando.
41.  Sahin O, Bakircioglu E, Serdarogullari M, Bayram A, Yayla S, Ulug U, Tosun SB, Bahceci M.: Infertility treatment of men with hypogonadotropic hypogonadism: combination of medical therapy with intracytoplasmic sperm injection. 28th Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE), Istanbul, Turkey, July 1-4, 2012.
42.  Bakircioglu M E, et al.: Micro TESE and ICSI outcomes of azoospermic men with hypogonadotropic hypogonadism after one year combined HCG and FSH treatment. 28th Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE), Istanbul, Turkey, July 1-4, 2012.
43.  Serdarogullari M, Bayram A, Bakircioglu ME, Ulug U, Erden H, Bahceci M.: Does extensive search and recovery affect ICSI outcomes in men with non-obstructive azoospermia. 68th Annual Meeting ASRM, 20-24 October 2012, San Diego
44.  
Bakircioglu E, et al.:Comparison of fresh versus frozen testicular sperm for intracytoplasmic sperm injection in patients with nonobstructive azoospermia. 110th Annual Meeting of the American Urological Association (AUA), New Orleans, May 15-May 20, 2015.
45.  Ranjith Ramasamy, M. Emre Bakırcıoğlu, Cenk Cengiz, Ender Karaca, Jason Scovell, Davut Pehlivan, Matthew Bainbridge, Richard A. Gibbs, James R. Lupski, Dolores J. Lamb. Whole-exome sequencing identifies novel homozygous mutation in NPAS2 in family with nonobstructive azoospermia.  110th Annual Meeting of the American Urological Association (AUA), New Orleans, May 15-May 20, 2015.
46.  
Through the quest of infertility gene:identification of two new genes involved in azoospermic and oligozoospermic patients by whole exome sequencing in Turkish consanguineous families. Okutman O., Muller J., Serdarogulları M., Gultomruk M., Skory V., GarnierJ.M.,  Gaucherot A., Bakircioglu E., Bahceci M., Goossens E., Charlet-Bergeurand N., Viville S. ESHRE Annual Meeting Lisbon, Portugal 14-17 June 2015.